Полное описание

The Extracellular Matrix: an Overview : сборник / edited by Robert P. Mecham. ; editor. R. Mecham. - Berlin ; Heidelberg : Springer, 2011. - on-line. - (Biology of Extracellular Matrix). - URL: http://dx.doi.org/10.1007/978-3-642-16555-9. - Загл. с экрана. - ISBN 978-3-642-16555-9. - Текст : электронный.
Содержание:
An overview of extracellular matrix structure and function --  Fibronectin and other adhesive glycoproteins --  Collagen: suprastructures and collagen fibril assembly.-  Asement membrane; Hyaluronan and the Aggregating Proteoglycans -- The small, leucine-rich proteoglycans -- Microfibrils and fibrillin -- Elastin -- Lysyl oxidase and lysyl oxidase-like enzymes -- The Fibulins -- Matricellular proteins.

ГРНТИ	УДК
31.27	57
34	58
62	59
76	60
	61

Рубрики:
life sciences
molecular biology
proteins
cell biology
life Sciences
cell Biology
protein Science
molecular Medicine

Аннотация: Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment.  Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
Доп. точки доступа:
Mecham, R.\editor.\

http://dx.doi.org/10.1007/978-3-642-16555-9

Держатели документа:
Государственная публичная научно-техническая библиотека России : 123298, г. Москва, ул. 3-я Хорошевская, д. 17 (Шифр в БД-источнике (KATBW): -661864124)

Шифр в сводном ЭК: c1380be8fabfe46989dba53c31277631

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