Полное описание

Woolford, J. A. The Double [3+2] Photocycloaddition Reaction : монография / by Jason A. Woolford. - Berlin ; Heidelberg : Springer Berlin Heidelberg, 2011. - on-line. - (Springer Theses). - URL: http://dx.doi.org/10.1007/978-3-642-22860-5. - Загл. с экрана. - ISBN 978-3-642-22860-5. - Текст : электронный.
Содержание:
Introduction and background -- Discovery of the double [3+2] photocycloaddition -- A brief discussion on fenestranes -- Investigation of the double [3+2] photocycloaddition reaction for the synthesis of fenestranes -- Attempted synthesis of a “criss-cross” double [3+2] photocycloadduct -- Attempts toward the synthesis of alternative structures via the double[3+2] photocycloaddition -- Conclusion -- Experimental -- References -- Appendix I.

ГРНТИ	УДК
31.15.27	544.4(043)

Рубрики:
chemistry
analytical chemistry
organic chemistry
medicinal chemistry
chemistry
organic Chemistry
medicinal Chemistry
analytical Chemistry

Аннотация: Jason Woolford's thesis describes for the first time, a double [3+2] photocycloaddition of alkenes onto aromatic rings. Modern synthetic chemistry relies on the ability of researchers to uncover new and more efficient ways of creating highly complex structures. This work describes a novel, environmentally friendly photochemical step that converts in one pot, trivial starting materials into otherwise difficult to contruct fenstrane frameworks.  The rigid cores of these frameworks have significant potential in drug design. Moreover, the novelty of this work overtakes many other methods for the creation of chiral centres. No less than seven chiral centres are created in the photochemical step together with the formation of four carbon-carbon bonds  and multifused rings. Jason's innovative work has been the subject of several publications in peer-reviewed journals.

http://dx.doi.org/10.1007/978-3-642-22860-5

Держатели документа:
Государственная публичная научно-техническая библиотека России : 123298, г. Москва, ул. 3-я Хорошевская, д. 17 (Шифр в БД-источнике (KATBW): -930126915)

Шифр в сводном ЭК: d53f30912b7e7eac826e506bb456dc45

Просмотр издания