Полное описание

Khojasteh, S. C. Drug Metabolism and Pharmacokinetics Quick Guide : руководство / by Siamak Cyrus Khojasteh, Harvey Wong, Cornelis E.C.A. Hop. - Electronic text data. - New York, NY : Springer, 2011. - URL: http://dx.doi.org/10.1007/978-1-4419-5629-3. - Загл. с экрана. - ISBN 978-1-4419-5629-3. - DOI 10.1007/978-1-4419-5629-3. - Текст : электронный.
Содержание:
Pharmacokinetics -- Drug Metabolizing Enzymes -- Oral Absorption -- Transporters -- Metabolism-Based Drug Interactions -- Biotransformation and Bioactivation -- Prediction of Human Pharmacokinetics -- Advances in Bioanalysis as it Relates to ADME -- ADME Properties and Their Dependence on Physicochemical Properties -- In Silico ADME Tools -- Approved Drugs -- Chemical Nomenclature.

ГРНТИ	УДК
61.45	615.2(03)

Рубрики:
medicine
pharmacy
pharmacology
biochemistry
biomedicine
pharmacology/Toxicology
pharmacy
biochemistry, general

Аннотация: Drug Metabolism and Pharmacokinetics Quick Guide is intended for broad readership of those interested in the discipline of drug metabolism and pharmacokinetics who work in drug discovery coming from the various disciplines, a background such as of medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics or toxicology. This guide provides, for the first time, a completely integrated look at multiple aspects of absorption, distribution, metabolism, and excretion (ADME) science in a summary format that is clear, concise and self-explanatory. This book will be used and referenced frequently as it provides detailed figures and tables for data interpretation. Also included are brief yet relevant factoids that bring a real-world dimension to the discussion of drug metabolism and pharmacokinetics. Key topics covered: 1. Pharmacokinetics 2. Drug metabolizing enzymes 3. Oral absorption 4. Transporters 5. Metabolism-based drug interactions 6. Biotransformation and bioactivation 7. Prediction of human pharmacokinetics 8. Bioanalysis 9. Physicochemical properties and drug-like properties 10. In silico tools 11. Approved drugs 12. Chemical nomenclature.
Доп. точки доступа:
Wong, H.
Hop, C.

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